Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN1 | Q92952 | 2/20 | 0.52 |
| ▸ | KCNN2 | Q9H2S1 | 2/20 | 0.52 |
| ▸ | KCNN3 | Q9UGI6 | 2/20 | 0.52 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.51 |
| ▸ | MECP2 | P51608 | 1/20 | 0.50 |
| ▸ | MBD2 | Q9UBB5 | 1/20 | 0.50 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.49 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.47 |
| ▸ | KDM4A | O75164 | 3/20 | 0.47 |
| ▸ | KDM4B | O94953 | 3/20 | 0.47 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.46 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24358276 | 1.00 | KCNN1 (0.52) | KCNN1KCNN2KCNN3SLC2A1MECP2 | |
| SCHEMBL24358259 | 0.92 | KCNN1 (0.58) | KCNN1KCNN2KCNN3SLC2A1MECP2 | |
| SCHEMBL30745673 | 0.92 | KCNN1 (0.58) | KCNN1KCNN2KCNN3SLC2A1MECP2 | |
| SCHEMBL30745703 | 0.90 | KCNN1 (0.56) | KCNN1KCNN2KCNN3SLC2A1MECP2 | |
| SCHEMBL24358274 | 0.90 | KCNN1 (0.56) | KCNN1KCNN2KCNN3SLC2A1MECP2 | |
| SCHEMBL24358277 | 0.87 | KCNN1 (0.51) | KCNN1KCNN2KCNN3SLC2A1MECP2 | |
| SCHEMBL30745690 | 0.87 | KCNN1 (0.51) | KCNN1KCNN2KCNN3SLC2A1MECP2 | |
| SCHEMBL24358254 | 0.83 | KCNN1 (0.54) | KCNN1KCNN2KCNN3SLC2A1MECP2 | |
| SCHEMBL30745764 | 0.83 | KCNN1 (0.54) | KCNN1KCNN2KCNN3SLC2A1MECP2 | |
| SCHEMBL24358281 | 0.81 | KCNN1 (0.56) | KCNN1KCNN2KCNN3SLC2A1MECP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240025891-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | CELGENE CORPORATION | 2024-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240025891-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | CYP8B1, PAH, INHA | KCNN1 4605/4885KCNN2 4592/4885KCNN3 4470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.