Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 6/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KCNK2 | O95069 | 3/20 | 0.42 |
| ▸ | KCNK10 | P57789 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29279995 | 1.00 | TRPV1 (0.47) | TRPV1PPARAPTPN2PTPN1PTPN7 | |
| SCHEMBL29279854 | 0.96 | TRPV1 (0.47) | TRPV1PPARAPTPN2PTPN1PTPN7 | |
| SCHEMBL29280132 | 0.91 | PTPN2 (0.51) | TRPV1PPARAPTPN2PTPN1PTPN7 | |
| SCHEMBL29280034 | 0.91 | PTPN2 (0.51) | TRPV1PPARAPTPN2PTPN1PTPN7 | |
| SCHEMBL29279899 | 0.91 | TRPV1 (0.55) | TRPV1PPARANR1H4EPHX2CCR5 | |
| SCHEMBL29279812 | 0.89 | PPARA (0.56) | TRPV1PPARANR1H4EPHX2LMNA | |
| SCHEMBL30745891 | 0.89 | PPARA (0.56) | TRPV1PPARANR1H4EPHX2LMNA | |
| SCHEMBL29280054 | 0.88 | TRPV1 (0.50) | TRPV1PPARANR1H4EPHX2CCR5 | |
| SCHEMBL29280075 | 0.88 | TRPV1 (0.50) | TRPV1PPARANR1H4EPHX2CCR5 | |
| SCHEMBL29280114 | 0.87 | TRPV1 (0.62) | TRPV1PPARANR1H4EPHX2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117682973-A | Sulfonamide compound and medical application thereof | 中国药科大学 | 2024-03-12 | — | — | CN | disclosed |