Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 4/20 | 0.44 |
| ▸ | ABL1 | P00519 | 8/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29279812 | 0.89 | PPARA (0.56) | SMN1; SMN2LMNAMEN1KMT2AMAPK1 | |
| SCHEMBL30745891 | 0.89 | PPARA (0.56) | SMN1; SMN2LMNAMEN1KMT2AMAPK1 | |
| SCHEMBL30745898 | 0.89 | MAPT (0.41) | SMN1; SMN2LMNAPPARAHPGD | |
| SCHEMBL29280081 | 0.87 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNAMEN1KMT2AMAPK1 | |
| SCHEMBL30745884 | 0.87 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNAMEN1KMT2AMAPK1 | |
| SCHEMBL29280039 | 0.85 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNAMEN1KMT2AMAPK1 | |
| SCHEMBL30745903 | 0.85 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNAMEN1KMT2AMAPK1 | |
| SCHEMBL29279851 | 0.84 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNAMEN1KMT2AMAPK1 | |
| SCHEMBL30745868 | 0.84 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNAMEN1KMT2AMAPK1 | |
| SCHEMBL29280017 | 0.82 | SMN1; SMN2 (0.65) | SMN1; SMN2LMNAMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117682973-A | Sulfonamide compound and medical application thereof | 中国药科大学 | 2024-03-12 | — | — | CN | disclosed |