Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 10/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 9/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 9/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | USP2 | O75604 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 8/20 | 0.51 |
| ▸ | TSHR | P16473 | 6/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29424710 | 0.96 | CYP2C9 (0.57) | CYP2C9CYP1A2CYP2D6ALDH1A1USP2 | |
| SCHEMBL29424690 | 0.86 | USP2 (0.70) | CYP2C9CYP1A2CYP2D6ALDH1A1USP2 | |
| SCHEMBL18517456 | 0.82 | CYP3A4 (0.46) | CYP2C9CYP1A2CYP2D6ALDH1A1USP2 | |
| SCHEMBL30484336 | 0.82 | CYP1A2 (0.45) | CYP2C9CYP1A2CYP2D6ALDH1A1USP2 | |
| SCHEMBL29891860 | 0.82 | CYP1A2 (0.65) | CYP2C9CYP1A2CYP2D6ALDH1A1USP2 | |
| SCHEMBL15986907 | 0.80 | CYP2C9 (0.44) | CYP2C9CYP1A2CYP2D6ALDH1A1USP2 | |
| SCHEMBL29424723 | 0.79 | TSHR (0.44) | CYP2C9CYP1A2CYP2D6ALDH1A1USP2 | |
| SCHEMBL19504452 | 0.78 | USP2 (0.56) | CYP2C9CYP1A2CYP2D6ALDH1A1USP2 | |
| SCHEMBL29700106 | 0.78 | CYP1A2 (0.45) | CYP2C9CYP1A2CYP2D6ALDH1A1USP2 | |
| SCHEMBL16075034 | 0.78 | USP2 (0.46) | CYP2C9CYP1A2CYP2D6ALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111936144-B | JAK inhibitors | 廖细斌 | 2023-12-22 | — | — | CN | claimed |
| CN-111936144-B | JAK inhibitors | 廖细斌 | 2023-12-22 | — | — | CN | disclosed |