Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 3/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | PRKCI | P41743 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | CCNK | O75909 | 1/20 | 0.31 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4217784 | 0.79 | AXL (0.42) | AXLNUDT1PRKCIADORA2AADORA1 | |
| Trifluoroacetic Acid SCHEMBL27742026 | 0.66 | KIT (0.37) | AXLCDK8RIPK1KDR | |
| SCHEMBL343400 | 0.66 | ADORA2A (0.57) | AXLNUDT1PRKCIADORA2AADORA1 | |
| SCHEMBL19153433 | 0.64 | ADORA2A (0.59) | AXLPRKCIADORA2AADORA1PDK2 | |
| SCHEMBL12040846 | 0.64 | ADORA2A (0.42) | AXLNUDT1PRKCIADORA2AADORA1 | |
| SCHEMBL5134352 | 0.63 | ADORA2A (0.44) | AXLNUDT1PRKCIADORA2AADORA1 | |
| SCHEMBL11286572 | 0.63 | AXL (0.39) | AXLNUDT1PRKCIADORA2AADORA1 | |
| SCHEMBL1565012 | 0.63 | AXL (0.38) | AXLNUDT1PRKCIADORA2AADORA1 | |
| SCHEMBL23889254 | 0.62 | ADORA2A (0.40) | AXLPRKCIADORA2AADORA1PIK3CA | |
| Ammonia Solution, Strong SCHEMBL18806383 | 0.61 | ADORA2A (0.43) | AXLPRKCIADORA2AADORA1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111936144-B | JAK inhibitors | 廖细斌 | 2023-12-22 | — | — | CN | claimed |
| CN-111936144-B | JAK inhibitors | 廖细斌 | 2023-12-22 | — | — | CN | disclosed |