Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 17/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 17/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 16/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 16/20 | 0.46 |
| ▸ | TSHR | P16473 | 12/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 8/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 6/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26984939 | 1.00 | CYP1A2 (0.46) | CYP1A2CYP3A4CYP2C19CYP2D6TSHR | |
| SCHEMBL26985424 | 0.83 | CYP1A2 (0.41) | CYP1A2CYP3A4CYP2C19CYP2D6TSHR | |
| SCHEMBL30746526 | 0.83 | CYP1A2 (0.41) | CYP1A2CYP3A4CYP2C19CYP2D6TSHR | |
| SCHEMBL22497892 | 0.82 | CYP1A2 (0.58) | CYP1A2CYP3A4CYP2C19CYP2D6TSHR | |
| SCHEMBL29377730 | 0.82 | CYP1A2 (0.58) | CYP1A2CYP3A4CYP2C19CYP2D6TSHR | |
| SCHEMBL26984969 | 0.81 | CYP1A2 (0.42) | CYP1A2CYP3A4CYP2C19CYP2D6TSHR | |
| SCHEMBL30746539 | 0.81 | CYP1A2 (0.42) | CYP1A2CYP3A4CYP2C19CYP2D6TSHR | |
| SCHEMBL30746592 | 0.81 | CYP1A2 (0.39) | CYP1A2CYP3A4CYP2C19CYP2D6TSHR | |
| SCHEMBL26984977 | 0.81 | CYP1A2 (0.39) | CYP1A2CYP3A4CYP2C19CYP2D6TSHR | |
| SCHEMBL31210360 | 0.80 | CYP1A2 (0.53) | CYP1A2CYP3A4CYP2C19CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120129678-A | Mitogen-activated protein kinase (MEK) inhibitors | 耐斯泰德医疗公司 | 2025-06-10 | — | — | CN | disclosed |
| EP-4551558-A2 | MITOGEN-ACTIVATED PROTEIN KINASE (MEK) INHIBITORS | Nested Therapeutics, Inc. (US) | 2025-05-14 | — | — | EP | disclosed |
| WO-2024010925-A2 | MITOGEN-ACTIVATED PROTEIN KINASE (MEK) INHIBITORS | NESTED THERAPEUTICS, INC. (US) | 2024-01-11 | — | — | WO | disclosed |