Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 10/20 | 0.36 |
| ▸ | KDR | P35968 | 10/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.35 |
| ▸ | GRK2 | P25098 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26985226 | 1.00 | HDAC3 (0.39) | HDAC3HDAC1HDAC6GAAL3MBTL1 | |
| SCHEMBL30746618 | 0.92 | HDAC3 (0.39) | HDAC3HDAC1HDAC6GAAL3MBTL1 | |
| SCHEMBL26985145 | 0.92 | HDAC3 (0.39) | HDAC3HDAC1HDAC6GAAL3MBTL1 | |
| SCHEMBL30746501 | 0.91 | HDAC1 (0.38) | HDAC3HDAC1HDAC6GAAL3MBTL1 | |
| SCHEMBL26985151 | 0.91 | HDAC1 (0.38) | HDAC3HDAC1HDAC6GAAL3MBTL1 | |
| SCHEMBL30746491 | 0.85 | SLC22A12 (0.36) | HDAC3HDAC1HDAC6GAAEGFR | |
| SCHEMBL26985172 | 0.85 | SLC22A12 (0.36) | HDAC3HDAC1HDAC6GAAEGFR | |
| SCHEMBL30746420 | 0.84 | RAF1 (0.42) | HDAC3HDAC1HDAC6GAAL3MBTL1 | |
| SCHEMBL26985095 | 0.84 | RAF1 (0.42) | HDAC3HDAC1HDAC6GAAL3MBTL1 | |
| SCHEMBL30746672 | 0.82 | MAPK1 (0.35) | GAAL3MBTL1EGFRKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120129678-A | Mitogen-activated protein kinase (MEK) inhibitors | 耐斯泰德医疗公司 | 2025-06-10 | — | — | CN | disclosed |
| EP-4551558-A2 | MITOGEN-ACTIVATED PROTEIN KINASE (MEK) INHIBITORS | Nested Therapeutics, Inc. (US) | 2025-05-14 | — | — | EP | disclosed |
| WO-2024010925-A2 | MITOGEN-ACTIVATED PROTEIN KINASE (MEK) INHIBITORS | NESTED THERAPEUTICS, INC. (US) | 2024-01-11 | — | — | WO | disclosed |