Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.52 |
| ▸ | BTK | Q06187 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29208870 | 1.00 | EGFR (0.52) | EGFRBTK | |
| SCHEMBL25001387 | 0.91 | EGFR (0.59) | EGFRBTK | |
| SCHEMBL29208873 | 0.89 | EGFR (0.44) | EGFRBTK | |
| SCHEMBL28533956 | 0.88 | EGFR (0.48) | EGFRBTK | |
| SCHEMBL25001815 | 0.86 | EGFR (0.46) | EGFRBTK | |
| SCHEMBL28535494 | 0.83 | EGFR (0.59) | EGFRBTK | |
| SCHEMBL25001608 | 0.83 | EGFR (0.64) | EGFRBTK | |
| SCHEMBL25002390 | 0.83 | EGFR (0.64) | EGFR | |
| SCHEMBL25820549 | 0.83 | EGFR (0.64) | EGFRBTK | |
| SCHEMBL29208871 | 0.82 | EGFR (0.39) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112538072-B | Aminopyrimidine EGFR inhibitors | 齐鲁制药有限公司 | 2024-02-06 | — | — | CN | disclosed |