Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.53 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1543531 | 1.00 | CYP11B1 (0.53) | CYP11B1MPOHSD11B1ALDH1A1HPGD | |
| SCHEMBL3620497 | 0.91 | CYP11B1 (0.47) | CYP11B1MPOHSD11B1ALDH1A1HPGD | |
| SCHEMBL12490223 | 0.81 | CYP11B1 (0.50) | CYP11B1MPOHSD11B1ALDH1A1PLCG1 | |
| SCHEMBL1007086 | 0.80 | CYP11B1 (0.53) | CYP11B1MPOHSD11B1ALDH1A1PLCG1 | |
| SCHEMBL6109965 | 0.80 | CYP11B1 (0.53) | CYP11B1MPOHSD11B1ALDH1A1HPGD | |
| SCHEMBL25347053 | 0.80 | CYP11B1 (0.53) | CYP11B1MPOHSD11B1ALDH1A1PLCG1 | |
| SCHEMBL129267 | 0.80 | CYP11B1 (0.53) | CYP11B1MPOHSD11B1ALDH1A1PLCG1 | |
| SCHEMBL929481 | 0.80 | CYP11B1 (0.53) | CYP11B1MPOHSD11B1ALDH1A1HPGD | |
| SCHEMBL1007759 | 0.80 | CYP11B1 (0.53) | CYP11B1MPOHSD11B1ALDH1A1PLCG1 | |
| Hydrochloric Acid SCHEMBL26104353 | 0.78 | CYP11B1 (0.51) | CYP11B1MPOHSD11B1ALDH1A1PLCG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023217230-A1 | KINESIN KIF18A INHIBITOR AND USE THEREOF | 上海湃隆生物科技有限公司 | 2023-11-16 | — | — | WO | disclosed |