Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.66 |
| ▸ | HTR2C | P28335 | 4/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1104626 | 1.00 | HTR2A (0.66) | HTR2AHTR2CKDM4EMAPTSIGMAR1 | |
| SCHEMBL12604657 | 0.95 | HTR2A (0.64) | HTR2AHTR2CKDM4EMAPTSIGMAR1 | |
| Hydrochloric Acid SCHEMBL6715292 | 0.78 | HTR2A (0.97) | HTR2AHTR2CKDM4EMAPTSIGMAR1 | |
| SCHEMBL18202164 | 0.78 | HTR2A (0.41) | HTR2AHTR2CKDM4EALOX15HSD17B10 | |
| SCHEMBL11163387 | 0.77 | HTR2A (0.56) | HTR2AHTR2CKDM4EMAPTSIGMAR1 | |
| SCHEMBL20080071 | 0.77 | CHRM2 (0.44) | HTR2AHTR2CKDM4EMAPTGAA | |
| SCHEMBL19960987 | 0.77 | HTR2A (0.42) | HTR2AHTR2CKDM4EMAPTRECQL | |
| SCHEMBL12563374 | 0.77 | HTR2C (0.42) | HTR2AHTR2CKDM4EMAPTRECQL | |
| SCHEMBL18202157 | 0.76 | HTR2C (0.41) | HTR2AHTR2CSIGMAR1GAAMAPK1 | |
| SCHEMBL18202165 | 0.76 | HTR2C (0.41) | HTR2AHTR2CALOX15HSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117069726-A | Synthesis method of [1,2-a ] indole polycyclic derivative | 兰州大学 | 2023-11-17 | — | — | CN | disclosed |