Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.56 |
| ▸ | PDE4A | P27815 | 1/20 | 0.56 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.56 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.55 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.55 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2073072 | 1.00 | CA1 (0.57) | CA1CA2PDPK1PDE4APDE4B | |
| SCHEMBL1442687 | 1.00 | CA1 (0.57) | CA1CA2PDPK1PDE4APDE4B | |
| SCHEMBL1441195 | 1.00 | CA1 (0.57) | CA1CA2PDPK1PDE4APDE4B | |
| SCHEMBL30752036 | 1.00 | CA1 (0.57) | CA1CA2PDPK1PDE4APDE4B | |
| SCHEMBL2358933 | 0.90 | HTT (0.68) | HTTTAS1R3TAS1R1TAS1R2ALDH1A1 | |
| SCHEMBL30751972 | 0.90 | HTT (0.68) | HTTTAS1R3TAS1R1TAS1R2ALDH1A1 | |
| SCHEMBL30046159 | 0.90 | HTT (0.68) | HTTTAS1R3TAS1R1TAS1R2ALDH1A1 | |
| SCHEMBL1441796 | 0.90 | HTT (0.68) | HTTTAS1R3TAS1R1TAS1R2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL19029871 | 0.89 | HTT (0.67) | HTTTAS1R3TAS1R1TAS1R2ALDH1A1 | |
| SCHEMBL4472558 | 0.87 | CA1 (0.54) | CA1CA2PDPK1PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112300172-B | Bruton tyrosine kinase inhibitors | 比奥根MA公司 | 2024-01-16 | — | — | CN | disclosed |