Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 12/20 | 0.49 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.49 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.46 |
| ▸ | AXL | P30530 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30753217 | 0.88 | NR4A2 (0.45) | NR4A2CREBBPMAP2K1AXLKDM4E | |
| SCHEMBL29196577 | 0.82 | KDM4E (0.53) | KDM4EKMT2ADYRK1A | |
| SCHEMBL31549255 | 0.76 | NR4A2 (0.53) | NR4A2CREBBPMAP2K1AXLKDM4E | |
| SCHEMBL926243 | 0.74 | NR4A2 (0.68) | NR4A2CREBBPMAP2K1AXLKDM4E | |
| SCHEMBL12768358 | 0.73 | PIM1 (0.47) | NR4A2CREBBPKDM4EGLAGAA | |
| SCHEMBL20509597 | 0.72 | KMT2A (0.41) | KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL15790576 | 0.72 | KMT2A (0.43) | KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29196591 | 0.71 | KDM4E (0.56) | KDM4EKMT2ADYRK1A | |
| SCHEMBL12768660 | 0.71 | NEK1 (0.41) | KDM4EGLAGAACHEK1MET | |
| SCHEMBL1527660 | 0.71 | PIM1 (0.44) | NR4A2CREBBPKDM4EGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117412966-A | Condensed pyridines for combating invertebrate pests | FMC公司 | 2024-01-16 | — | — | CN | disclosed |