SCHEMBL30753231

SCHEMBL30753231

OCCOCCOCCOCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
TSHR P16473 2/20 0.40
MAPK1 P28482 1/20 0.40
THRB P10828 1/20 0.32
HTT P42858 1/20 0.32
MAPT P10636 1/20 0.32
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16931684 1.00 MEN1 (0.44) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL7560039 1.00 MEN1 (0.44) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL28533000 0.96 TSHR (0.38) MEN1KMT2ATSHRMAPK1ALDH1A1
SCHEMBL7558529 0.96 TSHR (0.38) MEN1KMT2ATSHRMAPK1ALDH1A1
SCHEMBL7563966 0.96 TSHR (0.38) MEN1KMT2ATSHRMAPK1ALDH1A1
SCHEMBL7771401 0.96 TSHR (0.38) MEN1KMT2ATSHRMAPK1ALDH1A1
SCHEMBL28484103 0.94 TSHR (0.39) MEN1KMT2ATSHRMAPK1ALDH1A1
SCHEMBL8220639 0.92 MEN1 (0.48) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL8777932 0.87 TSHR (0.41) MEN1KMT2ATSHRMAPK1ALDH1A1
SCHEMBL30899126 0.85 MEN1 (0.34) MEN1KMT2ATSHRMAPK1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12097475-B2 Microfluidic system THE UNIVERSITY OF CHICAGO (US) 2024-09-24 US disclosed
US-20240192707-A1 MICROFLUIDIC SYSTEM THE UNIVERSITY OF CHICAGO 2024-06-13 US disclosed
US-20240160231-A1 MICROFLUIDIC SYSTEM THE UNIVERSITY OF CHICAGO 2024-05-16 US disclosed
US-11853087-B2 Microfluidic system THE UNIVERSITY OF CHICAGO (US) 2023-12-26 US disclosed