Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 17/20 | 0.54 |
| ▸ | PTGER4 | P35408 | 16/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30754089 | 1.00 | PTGER2 (0.54) | PTGER2PTGER4ABCB1ABCG2IDH1 | |
| SCHEMBL30754077 | 0.88 | PTGER4 (0.46) | PTGER2PTGER4ABCB1ABCG2 | |
| SCHEMBL30754106 | 0.88 | PTGER4 (0.46) | PTGER2PTGER4ABCB1ABCG2 | |
| SCHEMBL30754081 | 0.87 | PTGER4 (0.45) | PTGER2PTGER4ABCB1ABCG2 | |
| SCHEMBL31490043 | 0.84 | PTGER2 (0.52) | PTGER2PTGER4 | |
| SCHEMBL4082485 | 0.82 | PTGER2 (0.48) | PTGER2PTGER4 | |
| SCHEMBL30754114 | 0.82 | PTGER4 (0.45) | PTGER2PTGER4 | |
| SCHEMBL30754092 | 0.81 | PTGER4 (0.42) | PTGER2PTGER4 | |
| SCHEMBL4077381 | 0.80 | PTGER4 (0.43) | PTGER2PTGER4 | |
| SCHEMBL1057599 | 0.79 | PTGER4 (0.47) | PTGER2PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4565565-A1 | 1,2-SUBSTITUTED 3-OXOPYRAZOLIDINE DERIVATIVES AS PROSTAGLANDIN E2 RECEPTOR 4 (EP4) AGONISTS FOR THE TREATMENT OF GASTROINTESTINAL AND PULMONARY DISEASES | Nxera Pharma UK Limited (GB) | 2025-06-11 | — | — | EP | disclosed |
| WO-2024028601-A1 | 1,2-SUBSTITUTED 3-OXOPYRAZOLIDINE DERIVATIVES AS PROSTAGLANDIN E2 RECEPTOR 4 (EP4) AGONISTS FOR THE TREATMENT OF GASTROINTESTINAL AND PULMONARY DISEASES | HEPTARES THERAPEUTICS LIMITED (GB) | 2024-02-08 | — | — | WO | disclosed |