SCHEMBL30754181

SCHEMBL30754181

Cc1ccncc1-c1cn(-c2cccnc2)nc1C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP17A1 P05093 6/20 0.40
CYP1A2 P05177 5/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
RIPK2 O43353 1/20 0.40
TLR8 Q9NR97 1/20 0.40
MAPK1 P28482 1/20 0.40
LCK P06239 1/20 0.38
BTK Q06187 1/20 0.38
ALDH1A1 P00352 2/20 0.38
GRM4 Q14833 1/20 0.38
KDM4E B2RXH2 1/20 0.38
HPGD P15428 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HSD17B10 Q99714 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ADORA3 P0DMS8 1/20 0.38
IRAK4 Q9NWZ3 1/20 0.37
DHODH Q02127 1/20 0.37
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23234411 1.00 CYP17A1 (0.40) CYP17A1CYP1A2NPC1RAB9ARIPK2
SCHEMBL23234388 0.89 LCK (0.47) CYP17A1CYP1A2NPC1RAB9ARIPK2
SCHEMBL30754185 0.89 LCK (0.47) CYP17A1CYP1A2NPC1RAB9ARIPK2
SCHEMBL23234386 0.85 NPC1 (0.51) CYP1A2NPC1RAB9AMAPK1ALDH1A1
SCHEMBL23234396 0.83 CYP2A6 (0.43) NPC1RAB9ARIPK2TLR8MAPK1
SCHEMBL10267021 0.81 NPC1 (0.42) NPC1RAB9ARIPK2TLR8MAPK1
SCHEMBL27682302 0.80 CYP2A6 (0.47) NPC1RAB9ATLR8MAPK1ALDH1A1
SCHEMBL30754179 0.79 IRAK4 (0.45) NPC1RAB9ARIPK2TLR8MAPK1
SCHEMBL23234414 0.79 IRAK4 (0.45) NPC1RAB9ARIPK2TLR8MAPK1
SCHEMBL4933208 0.78 MAPK1 (0.41) NPC1RAB9ATLR8MAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112236421-B Pyrazole derivatives and pest control agents 组合化学工业株式会社 2023-12-26 CN disclosed