SCHEMBL30755035

SCHEMBL30755035

FC(F)(F)c1ccc(COC2CCC2)cc1

nearest known ligand 0.58

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 3/20 0.58
PRMT6 Q96LA8 3/20 0.58
NAAA Q02083 3/20 0.55
IDO1 P14902 2/20 0.52
MMP2 P08253 1/20 0.46
MMP13 P45452 1/20 0.46
KMT2A Q03164 1/20 0.45
TACR1 P25103 2/20 0.44
MAOB P27338 4/20 0.44
LIPG Q9Y5X9 1/20 0.43
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18615758 0.96 CARM1 (0.58) CARM1PRMT6NAAAIDO1MMP2
SCHEMBL2296456 0.85 CARM1 (0.54) CARM1PRMT6NAAAIDO1MMP2
SCHEMBL2299635 0.85 CARM1 (0.54) CARM1PRMT6NAAAIDO1MMP2
Hydrochloric Acid SCHEMBL381868 0.83 CARM1 (0.53) CARM1PRMT6NAAAIDO1MMP2
SCHEMBL12049739 0.82 CARM1 (0.70) CARM1PRMT6NAAAIDO1MMP2
SCHEMBL18003014 0.82 CARM1 (0.52) CARM1PRMT6NAAAIDO1MMP2
SCHEMBL18003555 0.81 CARM1 (0.51) CARM1PRMT6NAAAIDO1MMP2
SCHEMBL31071549 0.81 SLC6A4 (0.54) CARM1PRMT6NAAAIDO1MMP2
SCHEMBL30754913 0.80 CARM1 (0.62) CARM1PRMT6IDO1TACR1MAOB
SCHEMBL31381237 0.80 CARM1 (0.50) CARM1PRMT6NAAAIDO1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024010015-A1 PYRIMIDINE DERIVATIVES あすか製薬株式会社 2024-01-11 WO disclosed