Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8420493 | 0.78 | KDM4E (0.60) | S1PR4TSHRMEN1KMT2ANPSR1 | |
| SCHEMBL2429174 | 0.78 | TSHR (0.47) | S1PR4TSHRMEN1KMT2ANPSR1 | |
| SCHEMBL31437826 | 0.78 | KDM4E (0.60) | S1PR4TSHRMEN1KMT2ANPSR1 | |
| SCHEMBL11649440 | 0.76 | CSNK2A1 (0.60) | S1PR4TSHRMEN1KMT2ANPSR1 | |
| SCHEMBL7922054 | 0.75 | KDM4E (0.56) | S1PR4TSHRMEN1KMT2ANPSR1 | |
| SCHEMBL25216222 | 0.75 | HTR2A (0.35) | TSHRMEN1KMT2ANPSR1KDM4E | |
| SCHEMBL18704576 | 0.74 | KDM4E (0.57) | S1PR4TSHRMEN1KMT2ANPSR1 | |
| SCHEMBL6172282 | 0.74 | KDM4E (0.44) | S1PR4MEN1KMT2AKDM4EMAPT | |
| SCHEMBL5880864 | 0.74 | TSHR (0.57) | S1PR4TSHRMEN1KMT2ANPSR1 | |
| SCHEMBL2617363 | 0.74 | KDM4E (0.55) | S1PR4TSHRMEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117616013-A | Hydrogenated quinoxalines | 大塚制药株式会社 | 2024-02-27 | — | — | CN | disclosed |