SCHEMBL30757240

SCHEMBL30757240

CCOCc1cc(CO)ccc1-c1ccccc1S(=O)(=O)N(COC)c1noc(C)c1C

nearest known ligand 0.43

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
EDNRA P25101 11/20 0.43
AGTR1 P30556 3/20 0.43
EDNRB P24530 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL535104 1.00 EDNRA (0.43) EDNRAAGTR1EDNRB
SCHEMBL30171054 0.94 EDNRA (0.41) EDNRAAGTR1EDNRB
SCHEMBL5523918 0.94 EDNRA (0.41) EDNRAAGTR1EDNRB
SCHEMBL5521669 0.92 EDNRA (0.36) EDNRAAGTR1
SCHEMBL534996 0.92 EDNRA (0.43) EDNRAAGTR1EDNRB
SCHEMBL26688766 0.92 EDNRA (0.43) EDNRAAGTR1EDNRB
SCHEMBL30757327 0.92 EDNRA (0.43) EDNRAAGTR1EDNRB
SCHEMBL4291679 0.92 EDNRA (0.43) EDNRAAGTR1EDNRB
SCHEMBL15728331 0.90 EDNRA (0.42) EDNRAAGTR1EDNRB
SCHEMBL26688792 0.90 EDNRA (0.36) EDNRAAGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025094214-A1 Process for the preparation of 2-[4-[(2-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-2-(ethoxymethyl)phenyl]-N-(4,5-dimethyl-1,2-oxazol-3-yl) benzenesulfonamide and its intermediates thereof MSN LABORATORIES PRIVATE LIMITED, R&D CENTER (IN) 2025-05-08 WO disclosed
WO-2023224963-A1 DUAL-ACTING ANGIOTENSIN AND ENDOTHELIN RECEPTOR ANTAGONISTS ARIA PHARMACEUTICALS, INC. (US) 2023-11-23 WO disclosed