⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4556705 | 0.97 | — | — | |
| SCHEMBL57884 | 0.88 | — | — | |
| SCHEMBL2036809 | 0.85 | TSHR (0.38) | — | |
| SCHEMBL10718401 | 0.77 | TSHR (0.52) | — | |
| SCHEMBL128643 | 0.77 | TSHR (0.52) | — | |
| SCHEMBL129678 | 0.77 | TSHR (0.52) | — | |
| SCHEMBL8999819 | 0.77 | TSHR (0.52) | — | |
| SCHEMBL129761 | 0.77 | — | — | |
| SCHEMBL2836775 | 0.77 | TSHR (0.52) | — | |
| SCHEMBL14785905 | 0.77 | TSHR (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109415468-B | Electro-optical polymers | 国立研究开发法人情报通信研究机构 | 2024-06-07 | — | — | CN | claimed |
| WO-2023245161-A2 | CATIONIC NONRIBOSOMAL LIPOPEPTIDES AND METHODS OF USE THEREOF | THE ROCKEFELLER UNIVERSITY (US) | 2023-12-21 | — | — | WO | claimed |
| CN-105934438-A | Nucleotides for the treatment of liver cancer | 艾登尼克斯药业有限公司 | 2016-09-07 | — | — | CN | claimed |
| CN-102741455-B | Surface treatment membrane, metal surface treatment agent and metal surface treatment method | NIHON PARKERIZING | 2015-03-11 | — | — | CN | claimed |
| CN-104211716-A | Preparation method of rapamycin | NOVARTIS AG | 2014-12-17 | — | — | CN | claimed |
| CN-104024385-A | QUATERNIZED POLYETHERAMINES AND USE THEREOF AS ADDITIVES IN FUELS AND LUBRICANTS | BASF SE | 2014-09-03 | — | — | CN | claimed |
| CN-102741455-A | Surface treatment membrane, metal surface treatment agent and metal surface treatment method | NIHON PARKERIZING | 2012-10-17 | — | — | CN | claimed |
| CN-101626683-A | Compounds and pharmaceutical compositions for the treatment of viral infections | IDENIX PHARMACEUTICALS INC | 2010-01-13 | — | — | CN | claimed |
| CN-101374847-A | Process for the preparation of rapamycin | NOVARTIS AG (CH) | 2009-02-25 | — | — | CN | claimed |
| CN-101287727-A | Novel high affinity quinoline-based kinase ligands | SCHERING CORP (US) | 2008-10-15 | — | — | CN | claimed |
| CN-101171007-A | The use of rapamycin derivatives for the treatment and/or prevention of cardiovascular disorders | NOVARTIS AG (CH) | 2008-04-30 | — | — | CN | claimed |
| CN-1863868-A | Polyacetal resin composition | POLYPLASTICS CO (JP) | 2006-11-15 | — | — | CN | claimed |
| CN-1784212-A | Oral care methods and products | DMI BIOSCIENCES INC (US) | 2006-06-07 | — | — | CN | claimed |
| CN-1203899-C | Compounds with chelation affinity and selectivity for first transition series elements, and their use in medical therapy and diagenosis | CONCAT LTD (US) | 2005-06-01 | — | — | CN | claimed |
| US-6596687-B1 | For treatment of many inflammatory and autoimmune diseases | BIOGEN, INC. | 2003-07-22 | — | — | US | claimed |
| WO-2000020441-A2 | CYCLIC PEPTIDES AS ANTIFUNGAL AGENTS | ABBOTT LABORATORIES (US) | 2000-04-13 | — | — | WO | claimed |
| CN-1189105-A | Compounds with chelating affinity and selectivity for elements of the first transition series and their use in medical therapy and diagnosis | CONCAT LTD (US) | 1998-07-29 | — | — | CN | claimed |
| CN-1180358-A | Bridged indoles as matrix metalloprotease inhibitors | SYNTEX INC (US) | 1998-04-29 | — | — | CN | claimed |
| WO-1998006745-A1 | AMINO-LIPOPEPTIDE ANTIFUNGAL AGENTS | ABBOTT LABORATORIES (US) | 1998-02-19 | — | — | WO | claimed |
| CN-1137797-A | Rapamycin derivatives useful as immunosuppressants | SANDOZ LTD (CH) | 1996-12-11 | — | — | CN | claimed |