SCHEMBL307585

SCHEMBL307585

O=C1[CH]NCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3101885 0.82
SCHEMBL195172 0.80
SCHEMBL6053208 0.72
SCHEMBL280044 0.71
SCHEMBL20183688 0.71
SCHEMBL1870088 0.63
SCHEMBL1422550 0.61
SCHEMBL3102511 0.59
SCHEMBL4303564 0.59
SCHEMBL6233840 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 179 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8426447-B2 Spiro-tricyclic ring compounds as beta-secretase modulators and methods of use AMGEN INC. (US) 2013-04-23 US claimed
US-20090324580-A1 Use of Inhibitors of Scavenger Receptor Class Proteins for the Treatment of Infectious Diseases CENIX BIOSCIENCE GMBH (DE) 2009-12-31 US claimed
US-20090181966-A1 PGD2 receptor antagonists for the treatment of inflammatory diseases MILLENNIUM PHARMACEUTICALS, INC. (US) 2009-07-16 US claimed
EP-1740547-A1 PGD2 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES MILLENNIUM PHARMACEUTICALS, INC. (US) 2007-01-10 EP claimed
US-20050256158-A1 PGD2 receptor antagonists for the treatment of inflammatory diseases MILLENNIUM PHARMACEUTICALS, INC. 2005-11-17 US claimed
WO-2005100321-A1 PGD2 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES MILLENNIUM PHARMACEUTICALS, INC. (US) 2005-10-27 WO claimed
EP-0643329-B2 Radiation curable liquid composition, particularly for stereolithography VANTICO AG (CH) 2002-02-06 EP claimed
EP-0643329-B1 Radiation curable liquid composition, particularly for stereolithography CIBA GEIGY AG (CH) 1998-12-23 EP claimed
US-5629133-A POLYETHERSILOXANE BLOCK COPOLYMER CIBA-GEIGY CORPORATION (US) 1997-05-13 US claimed
US-5573889-A Process for adjusting the sensitivity to radiation of photopolymerizable compositions CIBA-GEIGY CORPORATION (US) 1996-11-12 US claimed
EP-0378144-A2 Photocurable compositions CIBA-GEIGY AG (CH) 1990-07-18 EP claimed
EP-0369212-A1 Derivatives of (hetero)aryloxynaphthalene, process, and (hetero)aryloxynaphthyl amines, and their use as herbicides BAYER AG (DE) 1990-05-23 EP claimed
EP-0347679-A1 1,7-Dioxynaphthalene derivatives BAYER AG (DE) 1989-12-27 EP claimed
EP-0342440-A1 Halogen-substituted phenoxybenzyl-(thi)ol derivatives BAYER AG (DE) 1989-11-23 EP claimed
EP-0338306-A2 Halogen-substituted phenoxybenzyl compounds BAYER AG (DE) 1989-10-25 EP claimed
EP-0315008-A2 Derivatives of (6-(hetero)aryloxy-naphthalin-2-yl-oxy)alcanoic acid BAYER AG (DE) 1989-05-10 EP claimed
EP-0313908-A2 Halogen-substituted phenoxyphenylpropionic acid derivatives BAYER AG (DE) 1989-05-03 EP claimed
EP-0309864-A1 Alpha-(5-aryloxy-naphthalen-1-yl-oxy)-propionic-acid derivatives BAYER AG (DE) 1989-04-05 EP claimed
EP-0272533-A2 Substituted phenoxypyridines BAYER AG (DE) 1988-06-29 EP claimed
EP-0154816-A2 Azo compounds containing sulfonic-acid groups BASF Aktiengesellschaft (DE) 1985-09-18 EP claimed