SCHEMBL30760100 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	CYP1A2	P05177	1/20	0.46

▸	POLB	P06746	1/20	0.46

▸	CYP3A4	P08684	1/20	0.46

▸	CYP2C19	P33261	1/20	0.46

▸	VHL	P40337	14/20	0.45

▸	HTRA1	Q92743	1/20	0.39

▸	ELOC	Q15369	5/20	0.38

▸	ELOB	Q15370	5/20	0.38

▸	MCL1	Q07820	4/20	0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30760075	0.89	CYP1A2 (0.45)	CYP1A2POLBCYP3A4CYP2C19VHL
SCHEMBL30760131	0.88	VHL (0.46)	VHLELOCELOB
SCHEMBL30759907	0.88	CYP1A2 (0.42)	CYP1A2POLBCYP3A4CYP2C19VHL
SCHEMBL30760060	0.87	CYP1A2 (0.46)	CYP1A2POLBCYP3A4CYP2C19VHL
SCHEMBL30760012	0.86	CYP1A2 (0.43)	CYP1A2POLBCYP3A4CYP2C19VHL
SCHEMBL31370926	0.85	VHL (0.62)	VHLELOCELOB
SCHEMBL30760000	0.85	CYP1A2 (0.45)	CYP1A2POLBCYP3A4CYP2C19VHL
SCHEMBL21421712	0.85	VHL (0.62)	VHLELOCELOB
SCHEMBL30760172	0.84	CYP1A2 (0.47)	CYP1A2POLBCYP3A4CYP2C19VHL
SCHEMBL30760034	0.83	POLB (0.46)	CYP1A2POLBCYP3A4CYP2C19VHL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2024040080-A1	KRAS INHIBITOR CONJUGATES	ERASCA, INC. (US)	2024-02-22	—	—	WO	disclosed