Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VHL | P40337 | 8/20 | 0.41 |
| ▸ | CMA1 | P23946 | 9/20 | 0.39 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30759956 | 0.92 | VHL (0.43) | VHLCMA1CASP1 | |
| SCHEMBL30760086 | 0.89 | VHL (0.47) | VHLCMA1 | |
| SCHEMBL30759998 | 0.89 | VHL (0.42) | VHLCMA1CASP1 | |
| SCHEMBL30760150 | 0.89 | VHL (0.44) | VHLCMA1CASP1 | |
| SCHEMBL30760163 | 0.88 | VHL (0.40) | VHLCMA1 | |
| SCHEMBL30760153 | 0.88 | VHL (0.40) | VHLCMA1CASP1 | |
| SCHEMBL30760136 | 0.88 | CYP1A2 (0.44) | VHLKDM4D | |
| SCHEMBL30759974 | 0.87 | VHL (0.45) | VHL | |
| SCHEMBL30759975 | 0.87 | VHL (0.45) | VHL | |
| SCHEMBL30760084 | 0.87 | VHL (0.42) | VHLCMA1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024040080-A1 | KRAS INHIBITOR CONJUGATES | ERASCA, INC. (US) | 2024-02-22 | — | — | WO | disclosed |