Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VHL | P40337 | 20/20 | 0.47 |
| ▸ | ELOC | Q15369 | 2/20 | 0.40 |
| ▸ | ELOB | Q15370 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30759978 | 0.91 | VHL (0.43) | VHLELOCELOB | |
| SCHEMBL30760183 | 0.91 | VHL (0.43) | VHLELOCELOB | |
| SCHEMBL30760003 | 0.90 | VHL (0.46) | VHLELOCELOB | |
| SCHEMBL30760110 | 0.89 | VHL (0.48) | VHLELOCELOB | |
| SCHEMBL30760148 | 0.89 | VHL (0.43) | VHLELOCELOB | |
| SCHEMBL30760114 | 0.88 | VHL (0.47) | VHLELOCELOB | |
| SCHEMBL30760152 | 0.87 | VHL (0.44) | VHLELOCELOB | |
| SCHEMBL30760049 | 0.87 | VHL (0.43) | VHLELOCELOB | |
| SCHEMBL27360151 | 0.86 | VHL (0.46) | VHL | |
| SCHEMBL30760137 | 0.86 | VHL (0.46) | VHLELOCELOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024040080-A1 | KRAS INHIBITOR CONJUGATES | ERASCA, INC. (US) | 2024-02-22 | — | — | WO | disclosed |