Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 3/20 | 0.33 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | PRKACA | P17612 | 1/20 | 0.31 |
| ▸ | PRKACG | P22612 | 1/20 | 0.31 |
| ▸ | PRKACB | P22694 | 1/20 | 0.31 |
| ▸ | AKT2 | P31751 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CIT | O14578 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30760090 | 0.75 | TRPV1 (0.40) | TRPV1 | |
| SCHEMBL8522790 | 0.74 | MAP2K4 (0.47) | PDK1CACNA1IMKNK1MKNK2ABL1 | |
| SCHEMBL15121659 | 0.73 | FFAR1 (0.40) | — | |
| SCHEMBL30760303 | 0.72 | HDAC4 (0.47) | ABL1DGAT1MAPK1 | |
| SCHEMBL18591818 | 0.72 | VHL (0.51) | — | |
| SCHEMBL19600019 | 0.72 | VHL (0.51) | — | |
| SCHEMBL1444985 | 0.72 | ANPEP (0.41) | SCN10A | |
| Hydrochloric Acid SCHEMBL19580800 | 0.71 | VHL (0.50) | — | |
| Hydrochloric Acid SCHEMBL31522618 | 0.71 | VHL (0.50) | — | |
| Hydrochloric Acid SCHEMBL18530425 | 0.71 | VHL (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024040080-A1 | KRAS INHIBITOR CONJUGATES | ERASCA, INC. (US) | 2024-02-22 | — | — | WO | disclosed |