Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | EPHB3 | P54753 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27292456 | 0.81 | NAPRT (0.38) | LMNAEPHB3KMT2AKDM4EALDH1A1 | |
| SCHEMBL30977391 | 0.79 | EPHB3 (0.56) | LMNAEPHB3KMT2AGAANR4A2 | |
| SCHEMBL405964 | 0.78 | EPHB3 (0.39) | LMNAMAPK1EPHB3KMT2ASTING1 | |
| SCHEMBL1325106 | 0.74 | CA12 (0.44) | LMNAEPHB3KMT2AGAANR4A2 | |
| SCHEMBL31383589 | 0.73 | GAA (0.44) | LMNAEPHB3KMT2AGAANR4A2 | |
| SCHEMBL13883203 | 0.73 | EPHB3 (0.40) | LMNAEPHB3KMT2AGAANR4A2 | |
| SCHEMBL29585395 | 0.73 | IRAK4 (0.44) | LMNAEPHB3KMT2ANR4A2KDM4E | |
| SCHEMBL3616031 | 0.73 | LCK (0.45) | LMNAEPHB3KMT2AKDM4EALDH1A1 | |
| SCHEMBL2059684 | 0.73 | KMT2A (0.42) | LMNAEPHB3KMT2ANR4A2POLB | |
| SCHEMBL18327124 | 0.72 | KMT2A (0.39) | LMNAKMT2AGAANR4A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247595-A1 | PYRAZOLOPYRAZINE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2023-12-28 | — | — | WO | disclosed |