Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | APEX1 | P27695 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | PPM1B | O75688 | 2/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.56 |
| ▸ | PPP1CC | P36873 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22579811 | 1.00 | POLB (0.61) | POLBAPEX1TDP1PPM1BPTPN1 | |
| SCHEMBL22623107 | 1.00 | POLB (0.61) | POLBAPEX1TDP1PPM1BPTPN1 | |
| SCHEMBL16728468 | 1.00 | POLB (0.61) | POLBAPEX1TDP1PPM1BPTPN1 | |
| SCHEMBL11247130 | 1.00 | POLB (0.61) | POLBAPEX1TDP1PPM1BPTPN1 | |
| SCHEMBL16728379 | 1.00 | POLB (0.61) | POLBAPEX1TDP1PPM1BPTPN1 | |
| SCHEMBL19387861 | 1.00 | POLB (0.61) | POLBAPEX1TDP1PPM1BPTPN1 | |
| SCHEMBL23626950 | 1.00 | POLB (0.61) | POLBAPEX1TDP1PPM1BPTPN1 | |
| SCHEMBL30901531 | 0.93 | PPM1B (0.49) | POLBAPEX1TDP1PPM1BPTPN1 | |
| SCHEMBL19318634 | 0.89 | POLB (0.69) | POLBAPEX1TDP1PPM1BPTPN1 | |
| SCHEMBL7594331 | 0.89 | POLB (0.69) | POLBAPEX1TDP1PPM1BPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117417355-A | Fused heterocyclic compound, preparation method and application thereof | 上海翊石医药科技有限公司 | 2024-01-19 | — | — | CN | disclosed |