SCHEMBL30760730

SCHEMBL30760730

c1cc(C[C@@H]2COCCN2)cc(-n2nccn2)c1

nearest known ligand 0.49

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HCRTR1 O43613 20/20 0.49
HCRTR2 O43614 20/20 0.49
CYP3A4 P08684 13/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16766890 1.00 HCRTR1 (0.49) HCRTR1HCRTR2CYP3A4
SCHEMBL14940503 1.00 HCRTR1 (0.49) HCRTR1HCRTR2CYP3A4
SCHEMBL14940506 1.00 HCRTR1 (0.49) HCRTR1HCRTR2CYP3A4
SCHEMBL16767114 0.84 HCRTR1 (0.49) HCRTR1HCRTR2CYP3A4
SCHEMBL16767113 0.84 HCRTR1 (0.49) HCRTR1HCRTR2CYP3A4
SCHEMBL16766769 0.82 HCRTR1 (0.41) HCRTR1HCRTR2CYP3A4
SCHEMBL16766770 0.82 HCRTR1 (0.41) HCRTR1HCRTR2CYP3A4
SCHEMBL17580405 0.81 HCRTR1 (0.48) HCRTR1HCRTR2CYP3A4
SCHEMBL17580406 0.81 HCRTR1 (0.48) HCRTR1HCRTR2CYP3A4
SCHEMBL17580094 0.81 HCRTR1 (0.48) HCRTR1HCRTR2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110612291-B Preparation of 2- ([ 1,2,3] triazol-2-yl) -benzoic acid derivatives 爱杜西亚药品有限公司 2024-02-13 CN disclosed