SCHEMBL30763402

SCHEMBL30763402

CN1CCN(c2nc(NCCS(=O)(=O)N(C)c3ccccc3)c3cc(Cl)ncc3n2)CC1

nearest known ligand 0.80

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HRH4 Q9H3N8 20/20 0.80
HTR3A P46098 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21633664 1.00 HRH4 (0.80) HRH4HTR3A
SCHEMBL21633573 0.91 HRH4 (0.66) HRH4HTR3A
SCHEMBL3758154 0.89 HRH4 (1.00) HRH4HTR3A
SCHEMBL23855484 0.88 HRH4 (0.72) HRH4HTR3A
SCHEMBL30763420 0.86 HRH4 (0.61) HRH4HTR3A
SCHEMBL21633742 0.86 HRH4 (0.61) HRH4HTR3A
SCHEMBL21686818 0.85 HRH4 (0.55) HRH4
SCHEMBL21633678 0.84 HRH4 (0.59) HRH4HTR3A
SCHEMBL21686896 0.84 HRH4 (0.79) HRH4HTR3A
SCHEMBL30763352 0.84 HRH4 (0.79) HRH4HTR3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112739699-B Pyridopyrimidine compounds as histamine H4 receptor inhibitors 费斯制药股份有限公司 2023-11-28 CN disclosed