Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SLC16A3 | O15427 | 7/20 | 0.51 |
| ▸ | SLC16A1 | P53985 | 7/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2463716 | 0.86 | GAA (0.48) | CYP1A2CYP3A4CYP2C9KDM4ELMNA | |
| SCHEMBL18583719 | 0.86 | CYP1A2 (0.46) | CYP1A2CYP3A4CYP2C9KDM4ELMNA | |
| SCHEMBL30605984 | 0.82 | SLC16A3 (0.44) | CYP1A2CYP3A4CYP2C9KDM4ELMNA | |
| SCHEMBL18583583 | 0.82 | CYP1A2 (0.43) | CYP1A2CYP3A4CYP2C9KDM4ELMNA | |
| SCHEMBL23142439 | 0.81 | CYP1A2 (0.51) | CYP1A2CYP3A4CYP2C9KDM4ELMNA | |
| SCHEMBL18583806 | 0.81 | CYP1A2 (0.51) | CYP1A2CYP3A4CYP2C9KDM4ELMNA | |
| SCHEMBL31295841 | 0.81 | CYP3A4 (0.43) | CYP1A2CYP3A4CYP2C9KDM4ELMNA | |
| SCHEMBL18583713 | 0.81 | CYP1A2 (0.51) | CYP1A2CYP3A4CYP2C9KDM4ELMNA | |
| SCHEMBL29295014 | 0.77 | CYP3A4 (0.39) | CYP1A2CYP3A4CYP2C9KDM4ELMNA | |
| SCHEMBL3622141 | 0.77 | MAPT (0.54) | CYP1A2CYP3A4CYP2C9KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119585263-A | Phenyl substituted dihydro Cai compounds and preparation and application thereof | 苏中药业集团股份有限公司 | 2025-03-07 | — | — | CN | disclosed |
| CN-119306715-A | Crystal of phenyl substituted dihydronaphthyridine compound and application thereof | 苏中药业集团股份有限公司 | 2025-01-14 | — | — | CN | disclosed |
| CN-119302952-A | Pharmaceutical preparation containing phenyl substituted dihydronaphthyridine compound and application thereof | 苏中药业集团股份有限公司 | 2025-01-14 | — | — | CN | disclosed |
| WO-2024022481-A1 | PHENYL-SUBSTITUTED DIHYDRONAPHTHYRIDINE COMPOUNDS, AND PREPARATION AND USE THEREOF | 苏中药业集团股份有限公司 | 2024-02-01 | — | — | WO | disclosed |