Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.68 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.59 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | DRD4 | P21917 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29278825 | 1.00 | KCNH2 (0.68) | KCNH2SIGMAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29204362 | 0.85 | KCNH2 (0.65) | KCNH2SIGMAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL30767205 | 0.85 | KCNH2 (0.65) | KCNH2SIGMAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL30767216 | 0.83 | KCNH2 (0.90) | KCNH2SIGMAR1SLC6A2SLC6A4DRD2 | |
| SCHEMBL13974919 | 0.83 | KCNH2 (0.70) | KCNH2SIGMAR1SLC6A2SLC6A4DRD2 | |
| SCHEMBL13965308 | 0.82 | KCNH2 (0.68) | KCNH2SIGMAR1SLC6A2SLC6A4DRD2 | |
| Hydrochloric Acid SCHEMBL7658247 | 0.82 | KCNH2 (0.88) | KCNH2SIGMAR1SLC6A2SLC6A4DRD2 | |
| SCHEMBL4525555 | 0.82 | KCNH2 (1.00) | KCNH2SIGMAR1DRD2 | |
| SCHEMBL10414971 | 0.81 | KCNH2 (0.80) | KCNH2SIGMAR1DRD2DRD4 | |
| SCHEMBL13995267 | 0.80 | KCNH2 (0.68) | KCNH2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117517545-A | Method for detecting trazodone hydrochloride related substances | 重庆锐恩医药有限公司 | 2024-02-06 | — | — | CN | claimed |
| CN-117517545-A | Method for detecting trazodone hydrochloride related substances | 重庆锐恩医药有限公司 | 2024-02-06 | — | — | CN | disclosed |