Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | ACP1 | P24666 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NCF1 | P14598 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21617054 | 1.00 | SMN1; SMN2 (0.45) | SMN1; SMN2NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL30764791 | 0.91 | SMN1; SMN2 (0.47) | SMN1; SMN2NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL21617089 | 0.91 | SMN1; SMN2 (0.47) | SMN1; SMN2NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL21617074 | 0.83 | NPC1 (0.43) | SMN1; SMN2NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL30764821 | 0.83 | NPC1 (0.43) | SMN1; SMN2NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL21617034 | 0.83 | XPO1 (0.35) | PIM1CTSSCTSKDHFRHRH4 | |
| SCHEMBL30764839 | 0.83 | XPO1 (0.35) | PIM1CTSSCTSKDHFRHRH4 | |
| SCHEMBL1702074 | 0.82 | NPC1 (0.50) | SMN1; SMN2NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL21617032 | 0.79 | SMN1; SMN2 (0.46) | SMN1; SMN2NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL30764845 | 0.79 | SMN1; SMN2 (0.46) | SMN1; SMN2NPC1RAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112566899-B | phenyl-N-quinoline derivatives for the treatment of RNA viral infections | ABIVAX公司 | 2024-01-30 | — | — | CN | disclosed |