Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 16/20 | 0.79 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23111988 | 1.00 | STING1 (0.79) | STING1MCL1MAPK1PARP15 | |
| SCHEMBL23630799 | 0.88 | STING1 (1.00) | STING1MCL1MAPK1PARP15 | |
| SCHEMBL23635813 | 0.88 | STING1 (0.76) | STING1MCL1MAPK1PARP15 | |
| SCHEMBL30697678 | 0.88 | STING1 (0.76) | STING1MCL1MAPK1PARP15 | |
| SCHEMBL23111980 | 0.88 | STING1 (0.65) | STING1MCL1MAPK1PARP15 | |
| SCHEMBL23635804 | 0.87 | STING1 (0.64) | STING1MCL1MAPK1PARP15 | |
| SCHEMBL23635897 | 0.85 | STING1 (0.78) | STING1MCL1MAPK1PARP15 | |
| SCHEMBL23111974 | 0.83 | STING1 (0.68) | STING1MCL1MAPK1 | |
| SCHEMBL23630792 | 0.82 | STING1 (0.67) | STING1MCL1PARP15 | |
| SCHEMBL23630791 | 0.81 | STING1 (0.65) | STING1MCL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112424181-B | Substituted condensed thiophenes as STING modulators | 希泰克斯特私人有限公司 | 2024-02-27 | — | — | CN | disclosed |