Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23112230 | 1.00 | HSD17B10 (0.73) | HSD17B10KDM4EGAALMNAMAPT | |
| SCHEMBL23630827 | 0.85 | HSD17B10 (1.00) | HSD17B10KDM4EGAALMNAMAPT | |
| SCHEMBL22908994 | 0.80 | HSD17B10 (0.49) | HSD17B10KDM4EGAALMNAMAPT | |
| SCHEMBL30765125 | 0.80 | HSD17B10 (0.49) | HSD17B10KDM4EGAALMNAMAPT | |
| SCHEMBL22905054 | 0.79 | HSD17B10 (0.48) | HSD17B10KDM4EGAALMNAMAPT | |
| SCHEMBL29443036 | 0.79 | HSD17B10 (0.48) | HSD17B10KDM4EGAALMNAMAPT | |
| SCHEMBL23635896 | 0.77 | HSD17B10 (0.57) | HSD17B10MAPTNPSR1FGFR1 | |
| SCHEMBL8241753 | 0.74 | HSD17B10 (0.54) | HSD17B10MAPTNPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL14398099 | 0.72 | HSD17B10 (0.51) | HSD17B10KDM4EMAPTNPSR1ALDH1A1 | |
| SCHEMBL8241340 | 0.71 | HSD17B10 (0.56) | HSD17B10KDM4EMAPTNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112424181-B | Substituted condensed thiophenes as STING modulators | 希泰克斯特私人有限公司 | 2024-02-27 | — | — | CN | disclosed |