SCHEMBL3076524

SCHEMBL3076524

c1ccc2nc(-c3cnc4ccccc4n3)cnc2c1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 8/20 0.63
RAB9A P51151 6/20 0.63
SMN1; SMN2 Q16637 3/20 0.63
BCHE P06276 1/20 0.63
KDM4E B2RXH2 4/20 0.61
ALDH1A1 P00352 4/20 0.61
HPGD P15428 3/20 0.61
MAPK10 P53779 2/20 0.61
HSD17B10 Q99714 2/20 0.61
GAA P10253 1/20 0.61
CASP1 P29466 1/20 0.61
CASP7 P55210 1/20 0.61
ADORA3 P0DMS8 3/20 0.59
ADORA2A P29274 1/20 0.59
ADORA1 P30542 1/20 0.59
PDE10A Q9Y233 1/20 0.56
CYP1A2 P05177 1/20 0.55
MAPT P10636 4/20 0.53
GPR3 P46089 1/20 0.52
MEN1 O00255 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29942654 1.00 NPC1 (0.63) NPC1RAB9ASMN1; SMN2BCHEKDM4E
SCHEMBL29966674 1.00 NPC1 (0.63) NPC1RAB9ASMN1; SMN2BCHEKDM4E
SCHEMBL29614829 1.00 NPC1 (0.63) NPC1RAB9ASMN1; SMN2BCHEKDM4E
SCHEMBL28395491 0.87 NPC1 (0.57) NPC1RAB9ASMN1; SMN2BCHEKDM4E
SCHEMBL4954320 0.87 NPC1 (0.81) NPC1RAB9ASMN1; SMN2BCHEKDM4E
SCHEMBL3686490 0.87 KDM4E (0.58) NPC1RAB9ASMN1; SMN2BCHEKDM4E
SCHEMBL30161801 0.87 KDM4E (0.58) NPC1RAB9ASMN1; SMN2BCHEKDM4E
SCHEMBL28473904 0.87 NPC1 (0.52) NPC1RAB9ASMN1; SMN2BCHEKDM4E
SCHEMBL29371290 0.85 NPC1 (0.71) NPC1RAB9ASMN1; SMN2BCHEKDM4E
SCHEMBL87505 0.85 NPC1 (0.71) NPC1RAB9ASMN1; SMN2BCHEKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107286089-B O-bicyclic amine compound, preparation method thereof and chiral product 中国科学院化学研究所 2020-03-10 CN disclosed
CN-102584869-B 2-nuclear magnetic resonance imaging contrast agent taking 2, 3-biquinoxaline as connecting body and preparation method thereof CHANGCHUN APPLIED CHEMISTRY 2014-01-08 CN disclosed
CN-102584869-B 2-nuclear magnetic resonance imaging contrast agent taking 2, 3-biquinoxaline as connecting body and preparation method thereof CHANGCHUN APPLIED CHEMISTRY 2014-01-08 CN disclosed
CN-102584869-A 2-nuclear magnetic resonance imaging contrast agent taking 2, 3-biquinoxaline as connecting body and preparation method thereof CHANGCHUN APPLIED CHEMISTRY 2012-07-18 CN disclosed
CN-102584869-A 2-nuclear magnetic resonance imaging contrast agent taking 2, 3-biquinoxaline as connecting body and preparation method thereof CHANGCHUN APPLIED CHEMISTRY 2012-07-18 CN disclosed
US-7833331-B2 Non-toxic corrosion-protection pigments based on cobalt UNIVERSITY OF DAYTON (US) 2010-11-16 US disclosed
US-7789958-B2 Non-toxic corrosion-protection pigments based on manganese UNIVERSITY OF DAYTON (US) 2010-09-07 US disclosed
US-20090163628-A1 NON-TOXIC CORROSION-PROTECTION PIGMENTS BASED ON COBALT STURGILL JEFFREY ALLEN 2009-06-25 US disclosed
US-7537663-B2 Corrosion-inhibiting coating UNIVERSITY OF DAYTON (US) 2009-05-26 US disclosed
US-7422793-B2 Non-toxic corrosion-protection rinses and seals based on rare earth elements UNIVERSITY OF DAYTON (US) 2008-09-09 US disclosed
US-20040020568-A1 Non-toxic corrosion-protection conversion coats based on rare earth elements DAYTON, UNIVERSITY OF 2004-02-05 US disclosed
WO-2004009869-A2 CORROSION-INHIBITING COATING FOR METAL SURFACES UNIVERSITY OF DAYTON (US) 2004-01-29 WO disclosed
US-20040016363-A1 CORROSION-INHIBITING COATING VENTURE LENDING & LEASING, IV, INC. 2004-01-29 US disclosed
US-20040016910-A1 Non-toxic corrosion-protection rinses and seals based on rare earth elements DAYTON, UNIVERSITY OF 2004-01-29 US disclosed
US-20040011252-A1 Non-toxic corrosion-protection pigments based on manganese UNIVERSITY OF DAYTON 2004-01-22 US disclosed
US-20030234063-A1 Non-toxic corrosion-protection conversion coats based on cobalt DAYTON, UNIVERSITY OF 2003-12-25 US disclosed
US-20030230363-A1 Non-toxic corrosion-protection rinses and seals based on cobalt UNIVERSITY OF DAYTON 2003-12-18 US disclosed
WO-2003060191-A2 NON-TOXIC CORROSION-PROTECTION CONVERSION COATINGES ABSED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
WO-2003060192-A1 NON-TOXIC CORROSION-PROTECTION RINSES AND SEALS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
WO-2003060019-A1 NON-TOXIC CORROSION PROTECTION PIGMENTS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed