Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | AHR | P35869 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | TNKS | O95271 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765533 | 1.00 | MAPT (0.55) | MAPTNPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL30765515 | 1.00 | MAPT (0.55) | MAPTNPC1SMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL30765518 | 0.98 | MAPT (0.53) | MAPTNPC1SMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL31558469 | 0.98 | MAPT (0.53) | MAPTNPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL30765796 | 0.89 | MEN1 (0.53) | MAPTNPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL30765598 | 0.86 | MAPT (0.51) | MAPTNPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL1102393 | 0.85 | MEN1 (0.53) | MAPTNPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7246583 | 0.85 | MAPT (0.58) | MAPTNPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL22787856 | 0.82 | MAPT (0.50) | MAPTNPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL25144257 | 0.81 | MAPT (0.49) | MAPTNPC1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| CN-119768164-A | Pharmaceutical compounds for treating complement-mediated disorders | 阿雷克森制药公司 | 2025-04-04 | — | — | CN | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |