Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.79 |
| ▸ | RAB9A | P51151 | 3/20 | 0.79 |
| ▸ | TTR | P02766 | 2/20 | 0.57 |
| ▸ | BCAT1 | P54687 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1283826 | 1.00 | NPC1 (0.79) | NPC1RAB9ATTRBCAT1ALDH1A1 | |
| SCHEMBL26304440 | 0.97 | NPC1 (0.74) | NPC1RAB9ATTRBCAT1ALDH1A1 | |
| SCHEMBL26317209 | 0.95 | NPC1 (0.72) | NPC1RAB9ATTRBCAT1ALDH1A1 | |
| SCHEMBL2043165 | 0.91 | NPC1 (0.69) | NPC1RAB9ATTRALDH1A1MAPT | |
| SCHEMBL26304441 | 0.90 | NPC1 (0.65) | NPC1RAB9ATTRALDH1A1MAPT | |
| SCHEMBL26317244 | 0.90 | NPC1 (0.74) | NPC1RAB9ATTRBCAT1ALDH1A1 | |
| SCHEMBL7110522 | 0.89 | NPC1 (0.69) | NPC1RAB9ATTRALDH1A1MAPT | |
| SCHEMBL10882826 | 0.88 | NPC1 (1.00) | NPC1RAB9ATTRALDH1A1MAPT | |
| SCHEMBL11285410 | 0.87 | NPC1 (0.70) | NPC1RAB9ATTRBCAT1ALDH1A1 | |
| SCHEMBL26317317 | 0.86 | NPC1 (0.65) | NPC1RAB9ATTRBCAT1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| CN-119768164-A | Pharmaceutical compounds for treating complement-mediated disorders | 阿雷克森制药公司 | 2025-04-04 | — | — | CN | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |