Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.58 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.58 |
| ▸ | FEN1 | P39748 | 1/20 | 0.58 |
| ▸ | CES2 | O00748 | 2/20 | 0.52 |
| ▸ | CES1 | P23141 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.46 |
| ▸ | WNT3A | P56704 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7797572 | 0.84 | KDM4E (0.58) | PTPN1ERCC5FEN1CES2CES1 | |
| SCHEMBL7791504 | 0.84 | KDM4E (0.58) | PTPN1ERCC5FEN1CES2CES1 | |
| SCHEMBL7797573 | 0.84 | KDM4E (0.58) | PTPN1ERCC5FEN1CES2CES1 | |
| Hydrochloric Acid SCHEMBL27418828 | 0.82 | KDM4E (0.56) | PTPN1ERCC5FEN1CES2CES1 | |
| Hydrochloric Acid SCHEMBL27418826 | 0.82 | KDM4E (0.56) | PTPN1ERCC5FEN1CES2CES1 | |
| SCHEMBL5847102 | 0.81 | PTPN1 (0.53) | PTPN1ERCC5FEN1CES2CES1 | |
| SCHEMBL28220980 | 0.80 | PTPN1 (0.49) | PTPN1ERCC5FEN1CES2CES1 | |
| SCHEMBL9431766 | 0.78 | PTPN1 (0.50) | PTPN1ERCC5FEN1CES2CES1 | |
| SCHEMBL27203850 | 0.78 | PTPN1 (0.50) | PTPN1ERCC5FEN1CES2CES1 | |
| SCHEMBL20508992 | 0.77 | PTPN1 (0.74) | PTPN1ERCC5FEN1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568960-A1 | BICYCLIC TETRAHYDROAZEPINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024033458-A1 | BICYCLIC TETRAHYDROAZEPINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2024-02-15 | — | — | WO | disclosed |