SCHEMBL30767883

SCHEMBL30767883

CCCCC[C@H]1CC[C@H](c2ccc(N)cc2C)CC1

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
OPRL1 P41146 8/20 0.42
GRM2 Q14416 3/20 0.38
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.38
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
ALDH1A1 P00352 1/20 0.34
CYP2C9 P11712 2/20 0.34
TSHR P16473 1/20 0.34
ACHE P22303 1/20 0.34
HTR4 Q13639 1/20 0.34
CYP3A4 P08684 1/20 0.33
CYP2C8 P10632 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
S1PR3 Q99500 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30767895 0.90 OPRL1 (0.45) OPRL1GAAMAPTMEN1KMT2A
SCHEMBL8945131 0.87 OPRL1 (0.38) OPRL1GRM2GAAMAPTMEN1
SCHEMBL8945279 0.86 OPRL1 (0.37) OPRL1GRM2GAAMAPTALDH1A1
SCHEMBL8945369 0.86 OPRL1 (0.37) OPRL1GRM2GAAMAPTALDH1A1
SCHEMBL8945231 0.86 OPRL1 (0.37) OPRL1GRM2GAAMAPTALDH1A1
SCHEMBL28760683 0.86 MAPT (0.40) OPRL1GRM2GAAMAPTMEN1
SCHEMBL9399878 0.84 GAA (0.43) OPRL1GRM2GAAMAPTMEN1
SCHEMBL9399342 0.83 OPRL1 (0.42) OPRL1GAAMAPTMEN1KMT2A
SCHEMBL29186352 0.83 OPRL1 (0.42) OPRL1GAAMAPTMEN1KMT2A
SCHEMBL30767882 0.83 OPRL1 (0.42) OPRL1GAAMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117534600-A Isothiocyano trans-cyclohexyl biphenyl liquid crystal compound, and preparation method and application thereof 武汉轻工大学 2024-02-09 CN disclosed