Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HASPIN | Q8TF76 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 2/20 | 0.32 |
| ▸ | TTK | P33981 | 2/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27034847 | 1.00 | HASPIN (0.42) | HASPINKMT2ATHRBALDH1A1GAA | |
| SCHEMBL30768106 | 1.00 | HASPIN (0.42) | HASPINKMT2ATHRBALDH1A1GAA | |
| SCHEMBL27034848 | 0.79 | HASPIN (0.42) | HASPINKMT2ATHRBALDH1A1GAA | |
| SCHEMBL15507768 | 0.79 | HASPIN (0.42) | HASPINKMT2ATHRBALDH1A1GAA | |
| SCHEMBL17056051 | 0.70 | TTK (0.44) | HASPINTTK | |
| SCHEMBL17056048 | 0.70 | TTK (0.43) | HASPINKMT2AMEN1TTK | |
| SCHEMBL17024320 | 0.70 | TTK (0.44) | TTK | |
| SCHEMBL27034877 | 0.70 | TP53 (0.35) | KMT2AALDH1A1GAAMEN1CYP1A2 | |
| SCHEMBL30768125 | 0.70 | TP53 (0.35) | KMT2AALDH1A1GAAMEN1CYP1A2 | |
| SCHEMBL24394072 | 0.69 | TTK (0.42) | HASPINPIM1TTKPIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4558502-A1 | AZA-QUINAZOLINE COMPOUNDS AND METHODS OF USE | Iambic Therapeutics, Inc. (US) | 2025-05-28 | — | — | EP | disclosed |
| CN-120051470-A | Azaquinazoline compounds and methods of use | 依安彼克医疗有限公司 | 2025-05-27 | — | — | CN | disclosed |
| WO-2024020419-A1 | AZA-QUINAZOLINE COMPOUNDS AND METHODS OF USE | IAMBIC THERAPEUTICS, INC. (US) | 2024-01-25 | — | — | WO | disclosed |