Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 20/20 | 0.46 |
| ▸ | CCND1 | P24385 | 18/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 13/20 | 0.46 |
| ▸ | CDK4 | P11802 | 11/20 | 0.46 |
| ▸ | CDK6 | Q00534 | 11/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.46 |
| ▸ | CDK9 | P50750 | 3/20 | 0.46 |
| ▸ | CDK1 | P06493 | 7/20 | 0.46 |
| ▸ | CCND3 | P30281 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27033522 | 1.00 | CDK2 (0.46) | CDK2CCND1CCNE1CDK4CDK6 | |
| SCHEMBL27034843 | 0.86 | CCNE1 (0.48) | CDK2CCND1CCNE1CDK4CDK6 | |
| SCHEMBL30761987 | 0.86 | CCNE1 (0.48) | CDK2CCND1CCNE1CDK4CDK6 | |
| SCHEMBL30762011 | 0.85 | CCNE1 (0.50) | CDK2CCND1CCNE1CDK4CDK6 | |
| SCHEMBL27034842 | 0.85 | CCNE1 (0.50) | CDK2CCND1CCNE1CDK4CDK6 | |
| SCHEMBL30761998 | 0.83 | CCNE1 (0.50) | CDK2CCND1CCNE1CDK4CDK6 | |
| SCHEMBL27034846 | 0.83 | CCNE1 (0.50) | CDK2CCND1CCNE1CDK4CDK6 | |
| SCHEMBL30761989 | 0.80 | CCNE1 (0.46) | CDK2CCND1CCNE1CDK4CDK6 | |
| SCHEMBL27060629 | 0.80 | CCNE1 (0.46) | CDK2CCND1CCNE1CDK4CDK6 | |
| SCHEMBL30761965 | 0.79 | CCNE1 (0.44) | CDK2CCND1CCNE1CDK4CDK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4558502-A1 | AZA-QUINAZOLINE COMPOUNDS AND METHODS OF USE | Iambic Therapeutics, Inc. (US) | 2025-05-28 | — | — | EP | disclosed |
| WO-2024020419-A1 | AZA-QUINAZOLINE COMPOUNDS AND METHODS OF USE | IAMBIC THERAPEUTICS, INC. (US) | 2024-01-25 | — | — | WO | disclosed |