Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTSR2 | O95665 | 1/20 | 0.65 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.65 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.65 |
| ▸ | TACR1 | P25103 | 1/20 | 0.58 |
| ▸ | DPP3 | Q9NY33 | 4/20 | 0.54 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.54 |
| ▸ | CTSB | P07858 | 2/20 | 0.54 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.52 |
| ▸ | GHSR | Q92847 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29733691 | 0.90 | NTSR2 (0.63) | NTSR2NTSR1SORT1TACR1CAPN1 | |
| SCHEMBL31242543 | 0.86 | NTSR2 (0.60) | NTSR2NTSR1SORT1TACR1CAPN1 | |
| SCHEMBL30974182 | 0.85 | NTSR2 (0.70) | NTSR2NTSR1SORT1TACR1DPP3 | |
| SCHEMBL31238561 | 0.85 | TACR1 (0.57) | NTSR2NTSR1SORT1TACR1DPP3 | |
| SCHEMBL30518127 | 0.84 | NTSR2 (0.69) | NTSR2NTSR1SORT1TACR1DPP3 | |
| SCHEMBL30945042 | 0.84 | CXCR4 (0.66) | NTSR2NTSR1SORT1CXCR4 | |
| SCHEMBL30866236 | 0.84 | NTSR2 (0.60) | NTSR2NTSR1SORT1TACR1DPP3 | |
| SCHEMBL31105542 | 0.84 | NTSR2 (0.64) | NTSR2NTSR1SORT1TACR1DPP3 | |
| SCHEMBL31657596 | 0.83 | NTSR2 (0.61) | NTSR2NTSR1SORT1TACR1DPP3 | |
| SCHEMBL31593371 | 0.83 | CXCR4 (0.60) | NTSR2NTSR1SORT1TACR1DPP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4547221-A2 | STABLE PEPTIDE COMPOSITIONS AND METHODS OF USE THEREOF FOR TREATMENT OF MODERATE/SEVERE DRY EYE-RELATED OCULAR SYMPTOMS | TearSolutions, Inc. (US) | 2025-05-07 | — | — | EP | disclosed |
| WO-2024006653-A2 | STABLE PEPTIDE COMPOSITIONS AND METHODS OF USE THEREOF FOR TREATMENT OF MODERATE/SEVERE DRY EYE-RELATED OCULAR SYMPTOMS | TEARSOLUTIONS, INC. (US) | 2024-01-04 | — | — | WO | disclosed |