Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.36 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27035494 | 1.00 | GSK3A (0.40) | GSK3AGSK3BPDE10AOPRL1PARP14 | |
| SCHEMBL30769972 | 0.85 | MAPK13 (0.41) | GSK3BMAPK14CASP3CDK9CASP7 | |
| SCHEMBL31197551 | 0.81 | IKBKE (0.35) | MAPK14CDK9KCNH2 | |
| SCHEMBL30769921 | 0.77 | MAPK13 (0.45) | MAPK14CDK9 | |
| SCHEMBL31197467 | 0.77 | PRMT5 (0.34) | MAPK14CDK9 | |
| SCHEMBL30769610 | 0.74 | PDE10A (0.42) | PDE10A | |
| SCHEMBL21118427 | 0.73 | — | — | |
| SCHEMBL30769935 | 0.72 | MAPK8 (0.32) | GSK3AGSK3BPARP14MAPK8 | |
| SCHEMBL27035450 | 0.72 | MAPK8 (0.32) | GSK3AGSK3BPARP14MAPK8 | |
| SCHEMBL27059926 | 0.72 | DAO (0.36) | GSK3AGSK3BMAPK8CASP3CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4558500-A1 | IMIDAZOPYRIDINE COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USES THEREOF | Sanofi (FR) | 2025-05-28 | — | — | EP | disclosed |
| WO-2024017977-A1 | IMIDAZOPYRIDINE COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USES THEREOF | SANOFI (FR) | 2024-01-25 | — | — | WO | disclosed |