SCHEMBL30770772

SCHEMBL30770772

[Ni+2].c1ccc(P(CCCP(c2ccccc2)c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
ESR1 P03372 4/20 0.33
ESR2 Q92731 4/20 0.33
KCNA3 P22001 1/20 0.31
CALM1 P0DP23 1/20 0.30
KDM4E B2RXH2 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL2831718 0.97 CYP3A4 (0.41) CYP3A4TDP1ESR1ESR2
Iodide SCHEMBL2831739 0.97 CYP3A4 (0.41) CYP3A4TDP1ESR1ESR2
Hydrochloric Acid SCHEMBL6327 0.97 CYP3A4 (0.41) CYP3A4TDP1ESR1ESR2KDM4E
SCHEMBL35092 0.97 CYP3A4 (0.45) CYP3A4TDP1ESR1ESR2KCNA3
SCHEMBL954340 0.94 CYP3A4 (0.43) CYP3A4TDP1ESR1ESR2KCNA3
SCHEMBL4255002 0.94 CYP3A4 (0.43) CYP3A4TDP1ESR1ESR2KCNA3
SCHEMBL31379074 0.94 CYP3A4 (0.43) CYP3A4TDP1ESR1ESR2KCNA3
SCHEMBL22749145 0.94 CYP3A4 (0.43) CYP3A4TDP1ESR1ESR2KCNA3
SCHEMBL22749132 0.94 CYP3A4 (0.43) CYP3A4TDP1ESR1ESR2KCNA3
SCHEMBL7934432 0.94 CYP3A4 (0.43) CYP3A4TDP1ESR1ESR2KCNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119421876-A Compounds and medicaments as DDR1 kinase inhibitors 日本新药株式会社 2025-02-11 CN disclosed
CN-119371371-A Compounds and compositions as PDGF receptor kinase inhibitors 日本新药株式会社 2025-01-28 CN disclosed
CN-115315421-B Compounds and compositions as PDGF receptor kinase inhibitors 日本新药株式会社 2024-12-03 CN disclosed
CN-117769546-A Allosteric ketene inhibitors of phosphoinositide 3-kinase (PI 3K) for the treatment of disease 佩特拉制药公司 2024-03-26 CN disclosed