Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR3 | P22607 | 9/20 | 0.40 |
| ▸ | FGFR2 | P21802 | 8/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.36 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.36 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL986239 | 0.80 | GRIN1 (0.47) | FGFR3 | |
| SCHEMBL984741 | 0.74 | MAPT (0.36) | F10 | |
| SCHEMBL986984 | 0.73 | MAPT (0.39) | F10 | |
| SCHEMBL984487 | 0.72 | GAA (0.41) | FGFR3 | |
| SCHEMBL3590092 | 0.70 | TDP1 (0.39) | — | |
| SCHEMBL986423 | 0.68 | NPC1 (0.44) | — | |
| SCHEMBL986302 | 0.68 | MAPT (0.44) | HSP90AB1 | |
| SCHEMBL986771 | 0.68 | NPC1 (0.56) | — | |
| SCHEMBL12930083 | 0.66 | NPC1 (0.42) | FGFR3FGFR2FGFR1 | |
| SCHEMBL13607904 | 0.66 | GRIN1 (0.46) | FGFR3FGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111757883-B | Novel inhibitors of bacterial glutaminyl cyclase for the treatment of periodontal disease and related diseases | 弗劳恩霍夫应用研究促进协会 | 2024-02-13 | — | — | CN | disclosed |