Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 4/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30771684 | 0.84 | PDE10A (0.45) | PDE10ARXFP1HRH3HTR3AHRH4 | |
| SCHEMBL30771676 | 0.84 | MAOB (0.44) | MAOBRXFP1HRH3HTR3AHRH4 | |
| SCHEMBL30340907 | 0.83 | CSNK1D (0.50) | MAOBRXFP1CSNK1DMAPK11MAPK14 | |
| SCHEMBL30340909 | 0.83 | MAOB (0.58) | MAOBRXFP1HRH3HTR3AHRH4 | |
| SCHEMBL27163778 | 0.82 | PDE10A (0.45) | PDE10AHRH3 | |
| SCHEMBL23603147 | 0.81 | PDE4A (0.46) | PDE10AHRH3KCNH2 | |
| Hydrochloric Acid SCHEMBL29830105 | 0.81 | PDE4A (0.46) | PDE10AHRH3KCNH2 | |
| Hydrochloric Acid SCHEMBL23578483 | 0.81 | PDE4A (0.46) | PDE10AHRH3KCNH2 | |
| SCHEMBL30771683 | 0.80 | MAOB (0.62) | PDE10AMAOBRXFP1MAPT | |
| SCHEMBL30771693 | 0.78 | PIM1 (0.51) | MAOBRXFP1HRH3HTR3AHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081304-B1 | ANTIBACTERIAL QUINOLINES | TECNIMEDE SOCIEDADE TECNICO MEDICINAL SA (PT) | 2024-03-06 | — | — | EP | claimed |