Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SYNJ2 | O15056 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 6S,9S-Roseoside SCHEMBL26979802 | 1.00 | POLB (0.61) | POLBGAAKDM4ERECQLBLM | |
| 6S,9S-Roseoside SCHEMBL26980152 | 1.00 | POLB (0.61) | POLBGAAKDM4ERECQLBLM | |
| 6S,9S-Roseoside SCHEMBL26980791 | 1.00 | POLB (0.61) | POLBGAAKDM4ERECQLBLM | |
| 6S,9S-Roseoside SCHEMBL26980041 | 1.00 | POLB (0.61) | POLBGAAKDM4ERECQLBLM | |
| 6S,9S-Roseoside SCHEMBL30771702 | 1.00 | POLB (0.61) | POLBGAAKDM4ERECQLBLM | |
| 6S,9S-Roseoside SCHEMBL30771713 | 1.00 | POLB (0.61) | POLBGAAKDM4ERECQLBLM | |
| 6S,9S-Roseoside SCHEMBL24481908 | 1.00 | POLB (0.61) | POLBGAAKDM4ERECQLBLM | |
| 6S,9S-Roseoside SCHEMBL27125678 | 1.00 | POLB (0.61) | POLBGAAKDM4ERECQLBLM | |
| 6S,9R-Roseoside SCHEMBL30205822 | 1.00 | POLB (0.61) | POLBGAAKDM4ERECQLBLM | |
| SCHEMBL29934898 | 0.86 | POLB (0.46) | POLBGAAKDM4ERECQLBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240000119-A1 | MEGASTIGMANE DERIVATIVE COMPOSITIONS AND METHODS FOR TASTE MODULATION | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2024-01-04 | — | — | US | disclosed |