Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 15/20 | 0.72 |
| ▸ | CDK12 | Q9NYV4 | 15/20 | 0.72 |
| ▸ | CCNT1 | O60563 | 8/20 | 0.72 |
| ▸ | CCNE1 | P24864 | 8/20 | 0.72 |
| ▸ | CDK2 | P24941 | 8/20 | 0.72 |
| ▸ | CDK9 | P50750 | 8/20 | 0.72 |
| ▸ | CDK7 | P50613 | 14/20 | 0.71 |
| ▸ | CCNH | P51946 | 14/20 | 0.71 |
| ▸ | MNAT1 | P51948 | 13/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21184583 | 1.00 | CCNK (0.72) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL21184622 | 0.97 | CCNK (0.70) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL21184345 | 0.90 | CCNK (0.68) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL21184354 | 0.90 | CCNK (0.68) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL21184351 | 0.88 | CCNK (0.77) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL21184347 | 0.87 | CCNK (0.71) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL21184444 | 0.87 | CCNK (0.70) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL21184350 | 0.87 | CCNK (0.72) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL21184447 | 0.86 | CCNK (0.66) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL21184348 | 0.85 | CCNK (0.85) | CCNKCDK12CCNT1CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3740206-B1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | SYROS PHARMACEUTICALS INC (US) | 2024-03-06 | — | — | EP | disclosed |