Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 7/20 | 0.76 |
| ▸ | NPC1 | O15118 | 9/20 | 0.70 |
| ▸ | RAB9A | P51151 | 8/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.70 |
| ▸ | HTT | P42858 | 2/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 5/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.62 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.62 |
| ▸ | RELA | Q04206 | 3/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | CASP3 | P42574 | 1/20 | 0.61 |
| ▸ | GFER | P55789 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10812660 | 0.90 | ROCK1 (0.62) | ABL1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL10923160 | 0.90 | ABL1 (0.61) | ABL1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28527743 | 0.86 | MAPT (0.76) | ABL1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29419362 | 0.85 | ABL1 (1.00) | ABL1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL15689011 | 0.85 | ABL1 (0.74) | ABL1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL18387706 | 0.85 | ABL1 (1.00) | ABL1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL21224243 | 0.84 | MAPT (0.61) | ABL1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2020280 | 0.84 | ABL1 (0.73) | ABL1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL30058875 | 0.84 | ABL1 (0.72) | ABL1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL17149218 | 0.83 | PHGDH (0.67) | ABL1NPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024027807-A1 | USE OF AMINOTHIAZOLE DERIVATIVE IN PREPARING DRUG FOR IMMUNOLOGICAL INFLAMMATION | 宁波亿诺药业有限公司 | 2024-02-08 | — | — | WO | disclosed |