Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 11/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 8/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | AGER | Q15109 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2471955 | 1.00 | HCRTR2 (0.42) | HCRTR2HCRTR1HDAC4MEN1KMT2A | |
| SCHEMBL3387269 | 0.87 | HCRTR2 (0.46) | HCRTR2HCRTR1HDAC4HDAC1HDAC6 | |
| SCHEMBL264270 | 0.85 | HCRTR2 (0.50) | HCRTR2HCRTR1ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL30775045 | 0.85 | HCRTR2 (0.50) | HCRTR2HCRTR1ALDH1A1KDM4ECYP3A4 | |
| Lithium SCHEMBL607039 | 0.83 | HCRTR2 (0.49) | HCRTR2HCRTR1ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL20781141 | 0.83 | HCRTR1 (0.38) | HCRTR2HCRTR1HDAC4HDAC1HDAC6 | |
| SCHEMBL607037 | 0.83 | HCRTR2 (0.49) | HCRTR2HCRTR1ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL30775081 | 0.83 | HCRTR1 (0.47) | HCRTR2HCRTR1 | |
| SCHEMBL3385652 | 0.83 | HCRTR1 (0.47) | HCRTR2HCRTR1 | |
| SCHEMBL19206989 | 0.81 | CCR1 (0.46) | HCRTR2HCRTR1ALDH1A1SMN1; SMN2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4688155-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | Bial-Portela & CA, S.A. (PT) | 2026-02-11 | — | — | EP | claimed |
| WO-2025023852-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - PORTELA & CA., S.A. (PT) | 2025-01-30 | — | — | WO | claimed |
| EP-4688155-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | Bial-Portela & CA, S.A. (PT) | 2026-02-11 | — | — | EP | disclosed |
| WO-2025023852-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - PORTELA & CA., S.A. (PT) | 2025-01-30 | — | — | WO | disclosed |
| CN-111315734-B | Substituted 2-azabicyclo [3.1.1] heptane and 2-azabicyclo [3.2.1] octane derivatives as orexin receptor antagonists | 克罗诺斯治疗有限公司 | 2024-03-08 | — | — | CN | disclosed |