Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19689491 | 1.00 | NR1H4 (0.86) | NR1H4HSD17B13 | |
| SCHEMBL26020036 | 0.93 | NR1H4 (0.85) | NR1H4HSD17B13 | |
| SCHEMBL19689516 | 0.93 | NR1H4 (1.00) | NR1H4HSD17B13 | |
| SCHEMBL29760494 | 0.93 | NR1H4 (1.00) | NR1H4HSD17B13 | |
| SCHEMBL19690419 | 0.92 | NR1H4 (0.89) | NR1H4HSD17B13 | |
| SCHEMBL32678083 | 0.92 | NR1H4 (0.89) | NR1H4HSD17B13 | |
| SCHEMBL31556468 | 0.92 | NR1H4 (0.87) | NR1H4HSD17B13 | |
| SCHEMBL29615216 | 0.91 | NR1H4 (0.88) | NR1H4HSD17B13 | |
| SCHEMBL22233105 | 0.90 | NR1H4 (0.74) | NR1H4HSD17B13 | |
| SCHEMBL19689492 | 0.90 | NR1H4 (1.00) | NR1H4HSD17B13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4534536-A1 | FXR (NR1H4) MODULATING COMPOUNDS | Gilead Sciences, Inc. (US) | 2025-04-09 | — | — | EP | disclosed |
| CN-113302190-B | FXR (NR 1H 4) modulating compounds | 吉利德科学公司 | 2024-10-18 | — | — | CN | disclosed |
| CN-117924266-A | Compounds that modulate FXR (NR 1H 4) | 吉利德科学公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-117924267-A | Compounds that modulate FXR (NR 1H 4) | 吉利德科学公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-109476636-B | Compounds that modulate FXR (NR 1H 4) | 吉利德科学公司 | 2024-01-09 | — | — | CN | disclosed |